1 Senior Technician with
consolidated experience in cell culture
We are looking for a motivated technician with consolidated experience in cell culture and good practice with different cell lines, stem cells and primary cells. She will be trained in human iPS cell generation, expansion and differentiation into several neural cell types and major responsabilities, research and duties will be:
- culture and quality check of human iPS cell cultures
- generation of iPS cell lines by reprogramming primary fibroblasts or blood cells from patients and healthy donors
- supervision of tissue & cell culture activities
- ensure that safe laboratory practices are followed, including the use and disposal of chemicals and hazardous materials
- provide technical support to postdoctoral associates, fellows and students
- develop new protocols for human iPS cell generation, differentiation and high-throughput applications.
The candidate should have documented long experience with tissue and cell culture activities, previous work with stem cells and/or human iPS cells will represent a plus but is not a prerequisite. Salary is already available for three years and will be commensurate with experience.
Applicants should submit a full CV with detailed description of her/his background and expertise together with contacts for recommendations to Vania Broccoli – firstname.lastname@example.org - email@example.com .
1 Junior Research Fellow
We are looking for a research fellow to work in the field of neurodegeneration and aging in Parkinson’s disease (PD) using iPSC-based in vitro modeling. The project is based on iPSC lines generated from patients with PD genetic forms including alpha-synuclein triplication and OPA1 mutations. He/she will carry out morphological, functional and genomic analysis of patient and genetic control iPSC-derived neurons to investigate the pathomolecular basis underlying PD-related neurodegeneration. Furthermore, this fellow will practice new procedures and settings for iPSC neuronal differentiation in order to obtain mature and functional human dopaminergic neurons and patterned co-cultures with glial and other neural cell types.
The ideal fellow might be an undergraduate student interested to PhD or an early post-doctoral fellow who, in either case, has already matured experience in neurobiology and neuroscience research. Good practice in cellular technologies and previous experience in neuroscience-related research projects are important pre-requisites for applying to this position.
Competitive salary will be offered based on the experience of the candidate.
Applicants should submit a full CV with detailed description of her/his background and expertise together with contacts for recommendations to Vania Broccoli – firstname.lastname@example.org - email@example.com
Epigenetic mechanisms of brain development
and neuroinfantile disorders
iPS cell technology for
in vitro disease modeling
Developing gene therapy approaches
for neurological disorders
Pathological mechanisms of neuronal cell
loss in Parkinson’s disease
Genetic strategies of
neuronal cell reprogramming
Novel therapies based on
gene editing technologies
Novel translational research
programs for Dravet syndrome
New therapies for